Research Activities

SIGMARIS research activities and grants under management

1. The Role of SPLA2-IIA as a Biomarker for the Diagnosis of Sepsis and Bacterial Infection in Adults - A Systematic Review, 2017 (UKMMC Fundamental Grant, FF-2017-049)

2. A Retrospective Study on the Clinical Probablity in Sepsis Identification by Using SIRS or qSOFA among the Patient of Emergency Department in Hospital Canselor Tuanku Muhriz, 2017  (UKMMC Fundamental Grant, FF-2017-158)

3. Factors Associated with Severe Dengue in Hospital Chancellor Tunku Muhriz - A Cross Sectional Study, 2017. (UKMMC Fundamental Grant, FF-2017-180)

4. Bedside Rapid Point-of-care Biosensor Kit for Sepsis and Bacterial Infection, 2017. (Protoytype Research Grant Skeme, PRGS/1.2017/STG05/ukm/03/1) 

5. A Study on The Appropriateness of Early Empirical Antibiotic Therapy in Predicting A 28-day Mortaliy Among Patient With Sepsis Syndrome Presented to Emergency Department in UKMMC, 2017 (Fundamental Grant, FF-2017-340)

6. Association between Shock Index and 28-Day Mortality Rate in Sepsis Patients who Presented to Emergency Department of Hospital Canselor Tuanku Muhriz, 2016 (UKMMC Fundamental Grant, FF-2016-156)

7. Evaluation of Dengue Dual Infection Score and Factors Associated with Dengue Severity in Emergency Department Universiti Kebangsaan Malaysia Medical Centre, 2016 (UKMMC Fundamental Grant, FF-2016-273)

8. A Comparison Study on Association between Comorbidites and Sepsis among Infected Patients Identified using qSOFA Score and SIRS Criteria in Emergency Department, Hospital Canselor Tuanku Muhriz, 2016 (UKMMC Fundamental Grant, FF-2016-322)

9. Evaluation Of Secretory Phospholipase A2 Group IIa (sPLA2-IIa) And Serum Procalcitonin (PCT) As A Predictor Of Sepsis In An Emergency Department Of A Teaching Hospital, 2015 (UKMMC Fundamental Grant, FF-2015-322)

10. Development of Sepsis Biosensor Kits, 2014. (Economic Transformation Programme Grant, ETP-2013-050)

11. Development Of Point-Of-Care Sepsis Biosensor Diagnostic Kits Using CD64 And PLA2-II, 2014 (UKMMC Fundamental Grant, FF-2014-150)

12. Development Of Monoclonal Antibodies Against Phospholipase A2 By Hybridoma Technology, 2014 (UKMMC Fundamental Grant, FF-2014-151)

13. Elucidating the role of sPLA2-IIa in eicosanoid pathway for the development of Sepsis, 2014 (Fundamental Research Grant Scheme, FRGS/1/2014/SKK01/UKM/03/3)

14. The evaluation of plasma lactate, CD64 and PLA2-II for the diagnostic and prognostic value in patients presenting to emergency department (ED) UKMMC in relation to 28-days mortality with sepsis, severe sepsis and septic shock, 2013. (Geran Galakan Penyelidik Muda, GGPM-2013-103)

15. Transforming pathogen identification in an era of the 4th industrial revolution: Development of a Decision-Making Algorithm for Rapid Pathogen Identification in the Clinical Microbiology Laboratory (Geran Untuk Pensyarah, GUP-2017-003)

16. Hemostatic Parameters and Biochemical Markers to Predict Severe Dengue Infection in Patients with “Warning Signs”, 2017 (Geran Galakan Penyelidik Muda, GGPM-2017-110)

17. Evaluation Of Mean Neutrophil Volume (MNV) And Immature To Total Neutrophil Ratio (IT Ratio) As A Marker For Bacterial Sepsis In Adults Patients Attending UKMMC, 2015 (UKMMC Fundamental Grant, FF-2015-116)

18. Development of a Discrete Event Simulation Model to Represent the Operational Parameters and Patients Flow Of Acute Clinical Services Provided at the Department of Emergency Medicine UKM Medical Centre, 2016. (UKMMC Fundamental Grant, FF-2015-246)

19. Evaluation Of Lactate Clearance For Risk Stratification Of Sepsis In Emergency Department, UKMMC, 2014. (UKMMC Fundamental Grant, FF-2014-109)

20. Diagnostic and prognostic evaluation of serum procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP) and plasma lactate in patients with sepsis in the critical care setting, 2013. (Geran Galakan Penyelidik Muda, GGPM-2013-102)

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