THE SURVIVING SEPSIS CAMPAIGN BUNDLE:
2018 UPDATE
The “sepsis bundle” has been central to the implementation of the Surviving Sepsis Campaign (SSC) from the first publication of its evidence-based guidelines in 2004 through subsequent editions. In response to the publication of “Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016”, a revised “hour-1 bundle” has been developed in 2018. The elements of the 2018 bundle, intended to be initiated within the first hour. The most important change in the revision of the SSC bundles is that the 3-h and 6-h bundles have been combined into a single “hour-1 bundle”. This reflects the clinical reality at the bedside of these seriously ill patients. Obtaining blood for measuring lactate and blood cultures, administration of fluids and antibiotics, and in the case of life-threatening hypotension, initiation of vasopressor therapy, are all begun immediately. It is important to note that there are no published studies that have evaluated the efficacy in important subgroups, including burns and immunocompromised patients.
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SURVIVING SEPSIS CAMPAIGN: INTERNATIONAL GUIDELINES FOR MANAGEMENT OF
SEPSIS AND SEPTIC SHOCK: 2016
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis and septic shock are major healthcare problems, affecting millions of people around the world each year, and killing as many as one in four (and often more). These clinical practice guidelines are a revision of the
2012 Surviving Sepsis Campaign (SSC) guidelines for the
management of severe sepsis and septic shock. These guidelines are appropriate for the sepsis patient in a
hospital setting. These guidelines are intended to be
best practice and not created to represent standard
of care.
Following table shows the comparison of recommendations from 2012 to 2016
THE SURVIVING SEPSIS CAMPAIGN BUNDLE:
2018 UPDATE
The “sepsis bundle” has been central to the implementation of the Surviving Sepsis Campaign (SSC) from the first publication of its evidence-based guidelines in 2004 through subsequent editions. In response to the publication of “Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016”, a revised “hour-1 bundle” has been developed in 2018. The elements of the 2018 bundle, intended to be initiated within the first hour. The most important change in the revision of the SSC bundles is that the 3-h and 6-h bundles have been combined into a single “hour-1 bundle”. This reflects the clinical reality at the bedside of these seriously ill patients. Obtaining blood for measuring lactate and blood cultures, administration of fluids and antibiotics, and in the case of life-threatening hypotension, initiation of vasopressor therapy, are all begun immediately. It is important to note that there are no published studies that have evaluated the efficacy in important subgroups, including burns and immunocompromised patients.
***********************************************************************
SURVIVING SEPSIS CAMPAIGN: INTERNATIONAL GUIDELINES FOR MANAGEMENT OF
SEPSIS AND SEPTIC SHOCK: 2016
2012 Surviving Sepsis Campaign (SSC) guidelines for the
management of severe sepsis and septic shock. These guidelines are appropriate for the sepsis patient in a
hospital setting. These guidelines are intended to be
best practice and not created to represent standard
of care.
Following table shows the comparison of recommendations from 2012 to 2016
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