15 August 2018
The BMJ
WHAT YOU NEED TO KNOW
• Sepsis is a syndrome of life threatening infection with organ dysfunction, and most guidelines do not advise use of corticosteroids to treat it in the absence of refractory shock
• Two new trials of corticosteroid treatment for sepsis came to differing conclusions
• Corticosteroids may reduce the risk of death by a small amount and increase neuromuscular weakness by a small amount, but the evidence is not definitive
• This guideline makes a weak recommendation for corticosteroids in patients with sepsis; both steroids and no steroids are reasonable management options
• Fully informed patients who value avoiding death over quality of life and function would likely choose corticosteroids
For Further Reading, please go to the follow link
https://www.bmj.com/content/362/bmj.k3284
Acknowledgement to The BMJ for permission for non profit reused.
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