SEPSIS 3 recommended the use of SOFA score to assess the organ failure status. However, the criteria are quite complex. We recommend the use of modified SOFA (MSOFA) to adapt to the local minimum setting.
The mortality rate was 9% for patients with no organ failure on admission, increasing to 82.6% for patients with four or more failing organs similar for both SOFA and MSOFA score.
When two organ systems were failing, as defined by a SOFA/MSOFA of 3 or 4, the presence of respiratory failure as one of the two failing systems was associated with a lower mortality rate than any other combination. For combinations of other organs, there was a narrow range of mortality (65% to 74%), and no identifiable pattern of increased risk with any specific organ.
SOFA score Mortality (noted: MSOFA have a similar mortality as SOFA.
SOFA Score
|
Mortality if initial score
|
Mortality if highest score
|
0-1
|
0.0%
|
0.0%
|
2-3
|
6.4%
|
1.5%
|
4-5
|
20.2%
|
6.7%
|
6-7
|
21.5%
|
18.2%
|
8-9
|
33.3%
|
26.3%
|
10-11
|
50.0%
|
45.8%
|
12-14
|
95.2%
|
80.0%
|
>14
|
95.2%
|
89.7%
|
Mean SOFA Score
|
Mortality
|
0-1.0
|
1.2%
|
1.1-2.0
|
5.4%
|
2.1-3.0
|
20.0%
|
3.1-4.0
|
36.1%
|
4.1-5.0
|
73.1%
|
>5.1
|
84.4%
|
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